Wnt糖蛋白是存在于多種生物體內的一種細胞外配體，Wnt作為形態發生素通過激發細胞內遠離信號發送區域的濃度依賴反應控制胚胎形態發育。Wnt通路調節動物發育過程中的多個重要環節，例如細胞增殖、細胞遷徙及細胞分化。Wnt蛋白通過自分泌或旁分泌作用與位于細胞膜上的受體相結合，激活細胞內信號通路調節靶基因的表達，對細胞的增殖、分化、遷移、極性化和凋亡起到重要作用。

StemRD W5A-H-100 WNT-5a,human,100ug 產品簡介
StemRD已研發出一種新穎的表達和純化諸如 StemRD W5A-H-100 WNT-5a,human,100ug 蛋白等“困難"蛋白的*方法。我們*的處理方法能得到純度和活性均于市場方法生產的WNT蛋白。StemRD W5A-H-100 WNT-5a,human,100ug 蛋白絕不含有現今市場普遍使用的WNT蛋白中含有的某些非特異性成分。
WNT-3a 干細胞生長分化因子是WNT 信號蛋白家庭的成員之一，在胚胎成長和成體組織維護方面起關鍵作用。WNT-3a 是典型的通過β-聯蛋白通路發送信號。已有規格的WNT-3a是一個包含328個氨基酸殘基的單鏈蛋白質。由于糖基化，WNT-3a 干細胞生長分化因子在非還原條件下用SDS-PAGE處理會明顯損失掉38-41 kDa分子量。StemRD公司生產的WNT-3a是用人體細胞系中Wnt-3a cDNA 在無蛋白培養基上過度表達得到。使用StemRD W5A-H-100 WNT-5a,human,100ug *的純化方法，區別于其它已發表的純化方法，提高蛋白純度。

StemRD W5A-H-100人源WNT-5a 蛋白因子，100ug產品特性
?StemRD W5A-H-100人源WNT-5a 蛋白因子，100ug 干細胞生長分化因子使用LC/MS 層析，純度大于98%，結構經過NMR驗證
?StemRD W5A-H-100人源WNT-5a 蛋白因子，100ug 干細胞生長分化因子生物活性認證：經過生物試驗驗證，優于其它同類型產品
? WNT-3a 干細胞生長分化因子是典型的通過β-聯蛋白通路發送信號

StemRD W5A-H-100人源WNT-5a 蛋白因子，100ug 保存方法
The lyophilized protein is stable for at least 6 months if stored at -80 degreeC. Reconstituted protein is stable for at least two weeks at 4 degree C, but should be stored in aliquots at -80 degree C for longer term. Avoid repeated freeze and thaw.

StemRD W5A-H-100 WNT-5a,human,100ug 產品英文描述
We express and purify StemRD StemRD W5A-H-100 WNT-5a,human,100ug proteins by using a proprietary process that is distinctive from the published protocol. Our method results in StemRD W5A-H-100 WNT-5a,human,100ug proteins that are purer and more active than market-leading products which have been associated with non-specific artifacts.
WNT-3a is a member of the WNT family of signaling proteins that play key roles in embryonic development and the maintenance of adult tissues. WNT-3a is a prototypic canonical WNT that signals through the β-catenin pathway. The predicted size of human WNT-3a is a monomeric protein containing 328 amino acid residues. Due to glycosylation, it migrates at an apparent molecular weight of 38 - 41 kDa on SDS-PAGE under non-reducing conditions. StemRD’s W5A-H-100 WNT-5a,human,100ug is produced from a human cell line overexpressing human Wnt-3a cDNA in protein-free medium.Purification is done by a proprietary process that is distinct from the published method.
WNT all compounds are:
1. >98% pure by LC/MS analysis, and structurally verified by NMR.
2. Bioactivity Certified: tested for biological activities, an advent-age over other supplies