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Source

Rabbit

Applications

WB,IHC,IF,ELISA

Reactivity

Human

Dilution

WB: 1:500 - 2000; IHC: 1:100 - 300; IF: 1:200 - 1000; ELISA: 1:20000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

COX4 Polyclonal Antibody detects endogenous levels of COX4 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human COX41. AA range:11-60

Uniprot No

P13073

Alternative names

COX4, COX IV

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Background

cytochrome c oxidase subunit 4I1(COX4I1) Homo sapiens Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes

Mol.Wt (Da)

19577

Concentration

1 mg/ml