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Source

Rabbit

Applications

WB,IHC,ELISA

Reactivity

Human

Dilution

IHC: 100-300.WB: 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

Acrosin Polyclonal Antibody detects endogenous levels of Acrosin protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from Acrosin . at AA range: 40-120

Uniprot No

P10323

Alternative names

ACR; ACRS; Acrosin

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

acrosin(ACR) Homo sapiens Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq, Jul 2008],

Other

ACR, Acrosin

Mol.Wt (Da)

45847

Concentration

1 mg/ml