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Source

Rabbit

Applications

WB

Reactivity

Human,Rat

Dilution

WB 1：500-2000

Storage

-20°C/1 year

Specificity

This antibody detects endogenous levels of ACPH at Human/Rat

Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen

Synthesized peptide derived from human ACPH

Uniprot No

P13798

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. [provided by RefSeq, Jul 2008],

Other

APEH D3F15S2 D3S48E DNF15S2, ACPH

Mol.Wt (Da)

80520

Concentration

1 mg/ml