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美國布魯克海文儀器公司>公司動態(tài)>BI-MwA分子量測量應(yīng)用案例

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BI-MwA分子量測量應(yīng)用案例

閱讀:668          發(fā)布時間:2014-12-16
 文獻(xiàn)名: A Water-Borne Adhesive Modeled after the Sandcastle Glue of P. californica
 
作者: Hui Shao, Kent N. Bachus, and Russell J. Stewart
Department of Bioengineering, University of Utah, Salt Lake City, UT 84112
 
摘要:Polyacrylate glue protein analogs of the glue secreted by Phragmatopoma californica, a marine polycheate, were synthesized with phosphate, primary amine, and catechol sidechains with molar ratios similar to the natural glue proteins. Aqueous mixtures of the mimetic polyelectrolytes condensed into liquid complex coacervates around neutral pH. Wet cortical bone specimens bonded with the coacervates, oxidatively crosslinked through catechol sidechains, had bond strengths nearly 40% of the strength of a commercial cyanoacrylate. The unique material properties of complex coacervates may be ideal for development of clinically useful adhesives and other biomaterials.
 
關(guān)鍵詞:adhesives, biomimetic, complex coacervation, phase behavior, polyelectrolytes
 

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