5-羥色胺受體2A抗體

英文名稱 5HT2A Receptor
中文名稱 5-羥色胺受體2A抗體
別    名 SR-2A; 5 HT 2; 5 HT 2A; 5 HT2 receptor; 5 HT2A; 5 hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; 5-hydroxytryptamine 2A receptor; 5-hydroxytryptamine receptor 2A; 5HT2A_HUMAN; HTR 2; HTR 2A; HTR2; HTR2A; Serotonin receptor 2A.
   
說 明 書 0.1ml  0.2ml  
研究領域 心血管  細胞生物  神經生物學  細胞膜受體  G蛋白偶聯受體  新陳代謝  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human 5HT2A Receptor
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.

Subunit:
Interacts with MPDZ and INADL. May interact with MPP3, PRDX6, DLG4, DLG1, CASK, APBA1 and MAGI2. xy-0899R    His tag(CT)聚組氨酸抗體g標簽抗體（C端）
xy-1737R    phospho-Histone H1.4 (Ser27)磷酸化組蛋白H1,4樣蛋白抗體
xy-2048R    HER2 receptorHER2受體抗體
xy-1691R    HCN4環化核苷酸調控陽離子通道蛋白亞型4
xy-15443R    HEATR8HEAT重復內含蛋白8蛋白抗體
xy-9070R    HN1L雄激素調節樣蛋白抗體
xy-9069R    HN1雄激素調節蛋白2抗體
xy-9703R    S100A18角化蛋白S100A18抗體
xy-4857R    Hepatitis C Virus NS4B丙型肝炎病毒NS4B抗體
xy-6459R    HNRPC異質性核糖核蛋白C1/C2抗體
xy-6979R    hnRNP R異質性核糖核蛋白R
xy-7612R    HIPK4同源相互作用蛋白激酶4抗體
xy-9843R    HCF2肝素輔助因子II抗體
xy-3530R    HIRA組蛋白替換精蛋白DGGR1抗體
xy-15412R    HAPLN4透明質酸及粘蛋白4抗體
xy-11348R    Hippocalcin神經細胞特異性鈣結合蛋白抗體
xy-8507R    Hairless無毛發蛋白抗體
xy-6935R    HAND2心臟和神經嵴衍生蛋白2抗體
xy-4707R    Acetyl-Histone H4(K16)乙酰化組蛋白H4(K16)抗體
xy-0750R    HLA G人類白細胞抗原G抗體（N端）
xy-0753R    HLA G人類白細胞抗原G抗體（C端）
xy-8326R    Hi95缺氧誘導基因95抗體
xy-8379R    HIP2泛素蛋白連接酶E2抗體
xy-7982R    HOXC9同源盒蛋白HOXC9抗體
xy-11630R    HCN2 + HCN4環化核苷酸調控陽離子通道蛋白亞型2/4抗體
xy-11851R    HELT轉錄因子HELT蛋白抗體
xy-11852R    HES6轉錄因子HES6抗體
xy-11853R    HMX2同源盒蛋白H6亞型2抗體
xy-11854R    HS6ST1硫酸乙酰肝素6腦苷脂轉硫酸酶1抗體
xy-11646R    Humanin神經保護肽HN抗體
xy-4646R    Capsid protein VP1大鼠細小病毒H-1株(H-1)抗體（N端）
xy-2946R    HAS1透明質酸合成酶1抗體
xy-5898R    HIF3 alpha缺氧誘導因子3α/HIF-3α抗體
xy-5899R    HIFPH4缺氧誘導因子脯氨酰4羥化酶抗體
xy-5888R    Hyaluronidase2透明質酸酶2/玻璃酸酶2抗體