精子相關抗原11B抗體

英文名稱 SPAG11B
中文名稱 精子相關抗原11B抗體
別    名 EP2; EP2C; EP2D; Epididymal protein 2; HE2; HE2C; Protein EP2; SPAG11; Sperm antigen HE2; Sperm associated antigen 11; Sperm associated antigen 11B.

說 明 書 0.2ml  
研究領域 細胞生物  發育生物學  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Chimpanzee, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 16kDa
細胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPAG11B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
SPAG11B is a 103 amino acid precursor protein that exists as four alternatively spliced isoforms, designated EP2A, EP2B, EP2C and EP2D, all of which are androgen-dependent, epididymis-specific secretory proteins that may play a role in sperm maturation and overall function. The gene encoding the SPAG11B precursor maps to a region on chromosome 8 that is near the ∫-defensin gene cluster and it is suggested that SPAG11B may exhibit functional characteristics (such as antimicrobial activity) that are similar to ∫-defensins. Human chromosome 8, on which the SPAG11B gene is localized, consists of nearly 146 million base pairs and houses more than 800 genes, some of which are associated with a variety of diseases and malignancies.

Function:
SPAG11B belongs to the SPAG11 family. The specific function of SPAG11B has not been determined, but it is thought to be involved in sperm maturation. It is specifically expressed in caput and proximal corpus of epididymis and is present in the epididymal epithelium and on the sperm surface, with a subacrosomal equatorial distribution on the sperm head. There are two named isoforms.

Subcellular Location:
Secreted

Database links:

Entrez Gene: 10407 Human

SwissProt: Q08648 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.xy-5857R    ADAMTS15整合素樣金屬蛋白酶與凝血酶15型抗體
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