突觸結合蛋白12抗體

英文名稱 Synaptotagmin XII
中文名稱 突觸結合蛋白12抗體
別    名 SRG1; Synaptotagmin 12; Synaptotagmin XII; Synaptotagmin-12; Syt12; SYT12_HUMAN; SytXII.
 
說 明 書 0.1ml  0.2ml  
研究領域 細胞生物  神經生物學  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Rabbit, Sheep, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
細胞定位 細胞漿 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Synaptotagmin XII (301-350aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.

Function:
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.

Subunit:
Homodimer. Can also form heterodimersxy-2656R    LIR-6白細胞免疫球蛋白樣受體6抗體
xy-2646R    LAG-3/CD223淋巴細胞活化基因-3抗體
xy-2647R    LAIR-1白細胞相關免疫球蛋白樣受體1抗體
xy-2650R    Langerin/CD207白細胞分化抗原CD207抗體
xy-2655R    LTB4-R2白三烯B4受體2抗體
xy-2648R    LAIR-2白細胞相關免疫球蛋白樣受體2抗體
xy-6069R    LLGL1相似腫瘤抑制基因HUGL抗體
xy-6319R    IL-1 Beta白介素1β抗體
xy-0814R    Beta-lactoglobulinβ-乳球蛋白抗體
xy-12150R    LPPR1脂質磷酸磷酸酶相關蛋白1/可塑性相關基因3抗體
xy-12141R    LRFN1神經突觸粘附樣分子1抗體
xy-9327R    LRCH1富含亮氨酸重復家庭蛋白1抗體
xy-9330R    LRCH4富含亮氨酸重復家庭蛋白4抗體
xy-0109R    Leptin receptor(long)瘦素受體抗體（長）
xy-1058R    LIF白血病抑制因子抗體
xy-1177R    Lingo-1Nogo受體反應蛋白抗體
xy-0738R    Livin凋亡抑制蛋白抗體
xy-0821R    laminin層粘連蛋白抗體
xy-0759R    Lpin1 proteinLpin1 抗體
xy-0760R    Lpin1 proteinLpin1 抗體
xy-0816R    Lysozyme溶菌酶抗體
xy-0484R    Iumbrokinase蚓激酶抗體
xy-0409R    Leptin瘦素抗體
xy-0410R    Leptin receptor瘦素受體抗體
xy-0109M    Leptin receptor(long)瘦素受體抗體（長）
xy-9708R    LCE1A晚期包膜蛋白1抗體
xy-6862R    LANPL富含亮氨酸樣酸性核蛋白抗體
xy-9709R    LCE2B晚期包膜蛋白2B抗體
xy-9711R    LIPK脂肪酶家庭成員K抗體
xy-1902R    Stathmin白血病相關蛋白18/癌蛋白18抗體