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轉錄因子sox9a抗體
英文名稱 Sox9a
中文名稱 轉錄因子sox9a抗體
別 名 Transcription factor sox9a; HMG box transcription factor Sox9a; Jef; Jellyfish; SRY box containing gene 9a; wu:fj17b12; zgc:111921; SOX9A_XENLA.
說 明 書 0.2ml
研究領域 細胞生物 細胞周期蛋白 轉錄調節因子 細胞分化 表觀遺傳學
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Cow, Sheep, Xenopus laevis, Danio rerio
產品應用 ELISA=1:500-1000 IHC-F=1:100-500 IF=1:50-200 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
細胞定位 細胞核 細胞漿
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from Xenopus laevis Sox9a
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產品介紹 background:
May be involved in chondrogenesis (cartilage development) during bone formation. Unlikely to play a role in sex determination but may function during testicular and ovarian differentiation (By similarity). Transcriptional activator. Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox8 and sox10 to induce neural crest progenitors. Induces sox10 expression downstream of wnt-signaling. Principally involved in development of the cranial neural crest, which is fated to form skeletal elements. Also required for otic placode specification during inner ear development.
Subunit:
Interacts with the sumoylation factors ube2i/ubc9 and sumo1.
Subcellular Location:
Nucleus. Cytoplasm (By similarity). Note=Restricted to the nucleus of Sertoli-like cells in the testis, but localizes to the cytoplasm of previlogenic oocytes in the ovary before being translocated into the nucleus of vilogenic oocytes (By similarity).xy-1248R S100BS100B蛋白抗體
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