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當(dāng)前位置:上海信裕生物科技有限公司>>抗體>>一抗>> 卵透明帶糖蛋白4抗體
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品 牌Abcam
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更新時間:2018-06-05 17:16:26瀏覽次數(shù):384次
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英文名稱 ZP4
中文名稱 卵透明帶糖蛋白4抗體
別 名 Processed zona pellucida sperm-binding protein 4; ZBP; Zona pellucida B protein; Zona pellucida glycoprotein 4; Zona pellucida protein B; Zona pellucida sperm binding protein 4; Zp-4; ZP1; ZP4; ZP4_HUMAN; ZPB.
說 明 書 0.2ml
研究領(lǐng)域 細(xì)胞生物 發(fā)育生物學(xué)
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Rabbit, Guinea Pig,
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
細(xì)胞定位 分泌型蛋白
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZP4
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產(chǎn)品介紹 background:
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. [provided by RefSeq, Jul 2008]
Function:
The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor.
Subcellular Location:
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xy-11688R Tau421微管相關(guān)蛋白Tau421抗體
xy-11980R CABP4瞬時受體電位通道蛋白4抗體
xy-7955R TPTE腫瘤/睪丸抗原44抗體
xy-7939R TACC1乳腺癌、胃癌抗原GA55抗體
xy-7924R TBRG4轉(zhuǎn)化生長因子β調(diào)節(jié)蛋白4抗體
xy-6914R TYK3酪氨酸蛋白激酶3抗體
xy-7911R phospho-TYK3(Tyr402)磷酸化酪氨酸蛋白激酶3抗體
xy-9049R TRPM1瞬時受體電位離子通道蛋白1抗體(M亞家族)
xy-9048R TRPM6瞬時受體電位離子通道蛋白6抗體(M亞家族)
xy-8059R TMEM2L跨膜蛋白2樣蛋白抗體
xy-11240R phospho-Tau protein(Ser202)磷酸化微管相關(guān)蛋白抗體
xy-11236R Lefty轉(zhuǎn)化生長因子β4抗體TGF β4
xy-11237R TCF12轉(zhuǎn)錄因子12抗體
xy-11262R TMP21跨膜轉(zhuǎn)運蛋白21抗體
xy-9531R TSBP睪丸特異蛋白抗體
xy-13769R THAP2THAP2蛋白抗體
xy-9047R TRPM5瞬時受體電位離子通道蛋白5抗體(M亞家族)
xy-9051R TRPM4瞬時受體電位離子通道蛋白4抗體(M亞家族)
xy-11309R TSARG2精子形成相關(guān)凋亡蛋白2抗體
xy-9009R Transportin 1轉(zhuǎn)運蛋白1抗體
xy-7103R THAP1核凋亡因子THAP1抗體
xy-7105R TIA1細(xì)胞毒顆粒相關(guān)蛋白TIA-1抗體
xy-7104R THYN1胸腺細(xì)胞核蛋白1抗體
xy-7551R TNFAIP3 interacting protein 3腫瘤壞死因子α誘導(dǎo)相互作用蛋白3抗體
xy-12097R TRPV3辣椒素受體3抗體
xy-12105R TEX261TEX261蛋白抗體
xy-2087R TSHR促甲狀腺素受體抗體
xy-3457R Phospho-TrkA(Tyr674 + Tyr675) + TrkB(Tyr706 + Tyr707)磷酸化酪氨酸激酶A抗體
xy-1444R TLR3Toll樣受體3抗體
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